Season 2 poster
20 episodes

Brilliant Minds - Season 2

First aired Sep 21, 2025Season 2

Seeing people, not patients. Zachary Quinto returns as Dr. Wolf, a brilliant neurologist at Bronx General whose compassionate approach leads to astounding breakthroughs in some of the world’s most puzzling psychological cases.

Episodes

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Episode 1

The Phantom Hook

5.0
Sep 22, 202543 min3 votes

Dr. Wolf helps an MMA fighter with mysterious symptoms. Dr. Pierce considers a career outside of Bronx General.

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Episode 2

The Contestant

5.0
Sep 29, 202543 min3 votes

A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General.

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Episode 3

The Pusher

5.5
Oct 6, 202543 min4 votes

Dr. Wolf and his team treat a young patient accused of a serious crime.

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Episode 4

Lady Liberty

7.5
Oct 13, 202543 min1 votes

Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.

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Episode 5

Once Upon a Time in America

7.0
Oct 20, 202543 min2 votes

When two patients arrive in critical condition, Dr. Wolf and Dr. Nichols must do whatever it takes to keep them alive.

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Episode 6

The Doctor's Graveyard

7.5
Oct 27, 202543 min2 votes

Dr. Wolf is haunted by a ghost from his past. A patient arrives at Bronx General who appears to have risen from the dead.

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Episode 7

The One That Got Away

7.7
Nov 3, 202543 min3 votes

A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.

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Episode 8

The Upside Down

8.1
Nov 17, 202543 min4 votes

On a flight gone wrong, one patient's life is literally turned upside down.

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Episode 9

The Fire Fighter

7.8
Nov 24, 202543 min3 votes

Wolf treats a heroic firefighter who struggles to share his ALS diagnosis with his family.

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Episode 10

The Resident

8.5
Dec 1, 202542 min3 votes

Dr. Wolf helps a ballerina recover after a mystery illness; the team tries to save Sam's life and get him on the transplant list; secrets are revealed at the hospital's annual holiday gala that change the course of the doctors' lives.

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Episode 11

The Boy Who Feels Everything

9.0
Jan 5, 202642 min2 votes

Dr. Wolf and the team come together as one of their own fights for their life.

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Episode 12

The Rider

7.8
Jan 12, 202642 min2 votes

A rugged cowboy struts into Bronx General with mysterious symptoms and brings the rodeo with him; Dr. Wolf develops a relationship with someone who has ties to his father.

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Episode 13

The Rabbit Hole

7.0
Jan 26, 202641 min1 votes

When a college student comes in with a life-threatening illness, Dr. Wolf and his team have to get acquainted with sorority life. Dr. Thorne treats a child who collapsed under mysterious circumstances.

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Episode 14

The Invisible Man

7.7
Feb 2, 202642 min3 votes

A grisly accident puts everyone at Bronx General in danger and leads to a shocking revelation about Dr. Wolf.

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Episode 15

The Missing Person

8.0
May 27, 202642 min1 votes

A Party Girl, who's on the run, is rushed into the hospital and our doctors have to figure out what exactly she's running from. When Wolf doesn't show up for his shift at the hospital, Carol-- worried about his mental health-- goes on a mission to find him.

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Episode 16

Senses

7.8
Jun 3, 202640 min2 votes

Wolf grapples with being a psych patient at Hudson Oaks and has a startling revelation. A renowned chef comes into Bronx General after a harrowing accident at his restaurant.

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Episode 17

Doctor, Interrupted

7.0
Jun 10, 202642 min1 votes

Wolf becomes fascinated with an unusual patient at Hudson Oaks, who displays signs of being possessed. Carol and Thorne help newlyweds who are struggling with their sex life.

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Episode 18

Through the Looking Glass

7.0
Jun 17, 202642 min1 votes

On his first day back at Bronx General, Wolf treats an ex-con who has a medical emergency during a hostage situation; Ericka and Charlie care for a newborn baby in the midst of a life-threatening illness.

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Episode 19

The Hero's Journey

7.0
Jun 24, 202642 min1 votes

Wolf treats an anxious teen boy who's faced with a terrifying procedure: awake brain surgery. Carol and Dana investigate possible corruption at Hudson Oaks.

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Episode 20

The Way Home

8.5
Jul 1, 202642 min2 votes

Wolf and Josh’s relationship is tested when they tackle a case that hits close to home. Carol and Thorne deal with their own medical mystery: a patient harboring a huge secret. Van returns and helps Ericka and Dana through their own personal crises.